Document Detail

Guglielmi detachable coils versus matrix coils: a comparison of the immediate posttreatment results of the embolization of 364 cerebral aneurysms in 307 patients: a single-center, single-surgeon experience.
MedLine Citation:
PMID:  17032854     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Matrix coils are based on Gugliemi detachable coils (GDC) but are covered with polyglycolic/polylactic acid. We present our experience regarding the immediate posttreatment results of aneurysm embolization using the 2 coil systems. PATIENTS: We embolized 219 aneurysms in 187 patients with the use of GDCs and 145 aneurysms in 120 patients with the use of Matrix coils. Age, sex distribution, unruptured aneurysm cases, and multiple aneurysm cases were similar in the 2 groups. The percentage of patients in severe clinical condition was significantly higher in the Matrix group. The mean aneurysm size was slightly larger in the GDC group but the mean neck size was larger in the Matrix group. RESULTS: Satisfactory occlusion (at least 90%) was achieved in 95.9% of GDC-treated aneurysms and in 98.6% of Matrix-treated aneurysms. Procedure-related complications occurred in 19.6% of GDC procedures and in 15.6% of the Matrix ones resulting in procedure-related mortality and morbidity of 3.7% and 2.7% for the GDC group and 2.5% and 1.7% for the Matrix group. In the GDC group, outcome was good (modified Rankin Scale 0-2) in 92.6% of patients with unruptured aneurysms, in 82.6% of patients with Hunt and Hess grade I-III, and in 20.5% of those with Hunt and Hess grade of IV-V. The respective figures were 95%, 85.7%, and 22.7% in the Matrix group. CONCLUSION: In our series, Matrix coils have yielded slightly better results regarding satisfactory occlusion rate and clinical outcome but these differences are not statistically significant and probably reflect our increased experience in aneurysm embolization during the period we used Matrix coils.
V Katsaridis; C Papagiannaki; C Violaris
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  AJNR. American journal of neuroradiology     Volume:  27     ISSN:  0195-6108     ISO Abbreviation:  AJNR Am J Neuroradiol     Publication Date:  2006 Oct 
Date Detail:
Created Date:  2006-10-11     Completed Date:  2007-01-12     Revised Date:  2008-02-14    
Medline Journal Info:
Nlm Unique ID:  8003708     Medline TA:  AJNR Am J Neuroradiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1841-8     Citation Subset:  IM    
Neurosurgical Department, Papanikolaou General Hospital, Thessaloniki, Greece.
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MeSH Terms
Aged, 80 and over
Aneurysm, Ruptured / therapy*
Coated Materials, Biocompatible*
Embolization, Therapeutic / instrumentation*
Equipment Design
Equipment Failure Analysis
Intracranial Aneurysm / therapy*
Lactic Acid*
Middle Aged
Polyglycolic Acid*
Prostheses and Implants*
Retrospective Studies
Subarachnoid Hemorrhage / therapy
Reg. No./Substance:
0/Coated Materials, Biocompatible; 0/Polymers; 0/polylactic acid-polyglycolic acid copolymer; 26009-03-0/Polyglycolic Acid; 50-21-5/Lactic Acid

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