Document Detail

Guar gum benefits duodenal ulcer patients by decreasing gastric acidity and rate of emptying of gastric contents 60 to 120 minutes postprandially.
MedLine Citation:
PMID:  6095709     Owner:  NLM     Status:  MEDLINE    
The effects of increasing the viscosity of a meal on postprandial acidity, acid load, and rate of emptying of gastric contents was studied in 15 duodenal ulcer patients in a double-blind manner by adding five gm of guar gum or placebo evenly to a test meal. The acidity of gastric juices was measured postprandially during a 120-min period using samples drawn via a nasogastric tube. Gastric emptying was measured via assessment of the degrees of dilution of polyethylene glycol added to the test meals. Guar gum decreased the total acid load, gastric juice acidity, and rates of emptying of gastric contents between 60 and 120 min postprandially, probably because of its effects on viscosity and neutralization of gastric acidity and may therefore be beneficial for duodenal ulcer patients.
E Harju
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American surgeon     Volume:  50     ISSN:  0003-1348     ISO Abbreviation:  Am Surg     Publication Date:  1984 Dec 
Date Detail:
Created Date:  1985-01-23     Completed Date:  1985-01-23     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370522     Medline TA:  Am Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  668-72     Citation Subset:  IM    
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MeSH Terms
Dietary Fiber / therapeutic use*
Double-Blind Method
Duodenal Ulcer / diet therapy,  metabolism*
Galactans / therapeutic use*
Gastric Acid / metabolism*
Gastric Emptying*
Intubation, Gastrointestinal
Mannans / therapeutic use*
Middle Aged
Plant Gums
Polyethylene Glycols / diagnostic use
Time Factors
Reg. No./Substance:
0/Galactans; 0/Mannans; 0/Plant Gums; 0/Polyethylene Glycols; 9000-30-0/guar gum

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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