Document Detail


The Guangzhou Twin Project: An Update.
MedLine Citation:
PMID:  23186635     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The Guangzhou Twin Registry is a population-based registry of twins residing in Guangzhou City. The initial registry database included 9,700 pairs of young twins recruited from the Official Household Registry of Guangzhou City. The registry is designed to provide a resource to identify the genetic and environmental causes of common diseases with an initial focus on eye diseases. From 2006 onward, phenotype and DNA collection have been completed for more than 1,200 twin pairs and their parents or siblings. Most of the young twins have come back for an annual examination of the progressive traits, such as refraction, ocular biometry, weight, and height. Genome-wide association scans have been completed recently. This article gives an update of the study design, cohort profile, previous findings, and future directions. Results from the Guangzhou Twin Project may contribute to the understanding of gene-environmental interplay for complex diseases in both adults and children.
Authors:
Yingfeng Zheng; Xiaohu Ding; Yanxian Chen; Mingguang He
Related Documents :
24898745 - New therapies for coronary artery disease: genetics provides a blueprint.
21395835 - Investigations on functional traits in simmental: 1. treatment costs for ten different ...
23925595 - Friedreich ataxia: executive control is related to disease onset and gaa repeat length.
21152795 - Cutaneous rosai-dorfman disease: a case report.
10365265 - Indications for pneumonectomy. pneumonectomy for benign disease.
19400745 - Recurrent burkholderia infection in patients with chronic granulomatous disease: 11-yea...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-11-28
Journal Detail:
Title:  Twin research and human genetics : the official journal of the International Society for Twin Studies     Volume:  -     ISSN:  1832-4274     ISO Abbreviation:  Twin Res Hum Genet     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101244624     Medline TA:  Twin Res Hum Genet     Country:  -    
Other Details:
Languages:  ENG     Pagination:  1-6     Citation Subset:  -    
Affiliation:
State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Are lead-free hunting rifle bullets as effective at killing wildlife as conventional lead bullets? A...
Next Document:  CH(4)/CO(2) ratios indicate highly efficient mhane oxidation by a pumice landfill cover-soil.