Document Detail

Growth of very low birth weight infants fed with milk from a human milk bank selected according to the caloric and protein value.
MedLine Citation:
PMID:  20835550     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To describe growth and clinical evolution of very low birth weight infants fed during hospital stay with milk from a human milk bank according to the caloric-protein value.
METHOD: Forty very low birth weight infants were included: 10 were fed milk from their own mothers (GI), and 30 were fed human milk bank > 700 cal/L and 2 g/dL of protein. Growth curves were adjusted using nonlinear regression to the measured growth parameters.
RESULTS: full enteral diet was reached in 6.3 days by GI and in 10.8 by GII; a weight of 2 kg was reached in 7.3 weeks for GI and in 7.8 for GII. In GI, 3/10 (33.3%) and in GII, 7/30 (23.3%) developed sepsis. Necrotizing enterocolitis did not occur in GI, but in 3/30 (10.0%) in GII. GI presented with urinary calcium > 4 mg/L in 1/10 (10.0%), urinary phosphorus (Pu) <1 mg/L in 10/10 (100%), and Ca/Cr >0.6 ratio in 1/10 (10.0%) of the cases; in GII, no children presented alterations of the urinary calcium or the Ca and Cr ratio, and Pu was <1 mg/L in 19/30 (63.3%). In terms of growth the 50th percentile for GI was a weight gain of 12.1 g/day (GI) vs. 15.8 g/day (GII), a length gain of 0.75 cm/week (GI) vs. 1.02 cm/week (GII), and a head circumference gain of 0.74 cm/week (GI) vs. 0.76 cm/week (GII).
CONCLUSIONS: Human milk bank allowed a satisfactory growth and good clinical evolution for very low birth weight infants.
Marisa da Matta Aprile; Rubens Feferbaum; Nerli Andreassa; Claudio Leone
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinics (São Paulo, Brazil)     Volume:  65     ISSN:  1980-5322     ISO Abbreviation:  Clinics (Sao Paulo)     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-09-13     Completed Date:  2011-11-03     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  101244734     Medline TA:  Clinics (Sao Paulo)     Country:  Brazil    
Other Details:
Languages:  eng     Pagination:  751-6     Citation Subset:  IM    
Pediatric Department, ABC Medical School - São Bernardo do Campo/SP, Brazil.
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MeSH Terms
Breast Feeding
Dietary Proteins / administration & dosage*
Energy Intake / physiology
Infant Nutritional Physiological Phenomena*
Infant, Newborn
Infant, Very Low Birth Weight / growth & development*
Length of Stay
Milk Banks* / standards
Milk, Human / chemistry*
Regression Analysis
Reg. No./Substance:
0/Dietary Proteins

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