| Growth of stenotic lesions after balloon angioplasty for pulmonary artery stenosis after arterial switch operation. | |
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MedLine Citation:
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PMID: 12633800 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Little is known about the growth potential of pulmonary stenotic lesions after balloon angioplasty (BA) in patients after the arterial switch operation. The aim of this study was to evaluate the growth potential of pulmonary stenotic lesions after BA and assess the midterm results of BA for pulmonary artery stenosis after the arterial switch operation. Thirty-seven patients who had undergone 52 procedures had repeat catheterization at a median of 43 years (range 1.2 to 9.3 ys) after BA. To adjust growth-related changes in the size of the pulmonary artery, the stenotic diameter was expressed as a percentage of normal (%N). An immediate increase of 63 +/- 45% in the stenotic diameter and a reduction of 51 +/- 33% in the pressure gradient occurred across the stenotic lesions after BA. The right ventricular-aortic systolic pressure ratio decreased from 0.67 +/- 0.24 to 0.51 +/- 0.12 after BA (p <0.0001). Compared with immediate data after BA, there was no significant change in the growth-adjusted diameter of the stenotic lesions (68 +/- 26 %N after BA vs 65 +/- 25 %N at follow-up, p = 0.08), and the pressure gradient (16 +/- 13 mm Hg after BA vs 20 +/- 21 mm Hg at follow-up, p = 0.10). The ventricular-aortic systolic pressure ratio also did not change (0.51 +/- 0.12 after BA vs 0.50 +/- 0.21 at follow-up, p = 0.57). Restenosis occurred in 3 of 26 vessels (12%) after successful BA in which the diameter increased >50% after BA. Our data suggest that pulmonary stenotic lesions after BA develop with age in growing children after the arterial switch operation, and the efficacy of the BA may be long lasting. |
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Authors:
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Yoshiki Mori; Toshio Nakanishi; Takao Niki; Chisato Kondo; Makoto Nakazawa; Yasuharu Imai; Kazuo Momma |
Publication Detail:
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Type: Clinical Trial; Journal Article |
Journal Detail:
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Title: The American journal of cardiology Volume: 91 ISSN: 0002-9149 ISO Abbreviation: Am. J. Cardiol. Publication Date: 2003 Mar |
Date Detail:
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Created Date: 2003-03-13 Completed Date: 2003-04-22 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0207277 Medline TA: Am J Cardiol Country: United States |
Other Details:
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Languages: eng Pagination: 693-8 Citation Subset: AIM; IM |
Affiliation:
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Pediatric Cardiology, The Heart Institute of Japan, Tokyo Women's Medical University, Tokyo, Japan. moriy@d7.dion.ne.jp |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Angioplasty, Balloon / adverse effects* Child Child, Preschool Female Follow-Up Studies Humans Infant Male Middle Aged Outcome Assessment (Health Care) Postoperative Complications* Pulmonary Artery / growth & development*, radiography, surgery* Pulmonary Valve Stenosis / etiology*, radiography, surgery* Recurrence Reoperation Time Factors Treatment Failure |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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