| Growth rate of corpus callosum in very premature infants. | |
| | |
MedLine Citation:
|
PMID: 16286423 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND AND PURPOSE: It is desirable to develop a bedside method for assessing cerebral development in the very premature infant to monitor the effectiveness of interventions aimed at improving cerebral development. Our aim was to describe the growth trajectory of the corpus callosum (CC) on cranial sonography in very premature infants. METHODS: We recruited 100 very-low-birth-weight infants admitted to a single regional level III neonatal intensive care unit from November 1998 to November 2000. Cranial sonography images of the CC were obtained for 64 (32 boys) infants (mean gestational age, 28 weeks; range, 23-33 weeks) in the first week of life and at term equivalency. The growth rate of the CC was compared in the 64 study infants to the expected growth rate of 0.20-0.27 mm/day from antenatal data and correlated with clinical outcome at 2 years of age by using Mental Development Index (MDI) and Psychomotor Development Index (PDI). RESULTS: The average growth rate of the CC was half of that expected from antenatal data. Mean growth rates were similar for all gestational ages (mean, 0.11 mm/day; range, 0.05-0.29; P = .4). The CC at term equivalency was longer for those in MDI class 2 (mean, 44.3 mm) compared with MDI class 3 (mean 40.2 mm; P = .003) as well as for PDI class 2 versus 3 (P = .017). CONCLUSION: Measurement of the length of the CC at cranial sonography is reproducible. Those with poorer neurodevelopmental outcomes have a shorter CC at term equivalency. The CC grows at a much lower rate postnatally than in utero among very premature infants. |
| | |
Authors:
|
Nigel G Anderson; Isabelle Laurent; Nick Cook; Lianne Woodward; Terrie E Inder |
Related Documents
:
|
17640333 - Radiographic closure time of appendicular growth plates in the icelandic horse. 10914953 - Foetal size to final height. 2816073 - Birth-spacing in rural yangoru, 1970-1987. |
Publication Detail:
|
Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: AJNR. American journal of neuroradiology Volume: 26 ISSN: 0195-6108 ISO Abbreviation: AJNR Am J Neuroradiol Publication Date: 2005 Nov-Dec |
Date Detail:
|
Created Date: 2005-11-15 Completed Date: 2006-02-13 Revised Date: 2008-02-14 |
Medline Journal Info:
|
Nlm Unique ID: 8003708 Medline TA: AJNR Am J Neuroradiol Country: United States |
Other Details:
|
Languages: eng Pagination: 2685-90 Citation Subset: IM |
Affiliation:
|
Department of Radiology, Christchurch Hospital, Christchurch, New Zealand. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Corpus Callosum
/
growth & development*,
radiography,
ultrasonography Female Gestational Age Humans Infant, Newborn Infant, Premature* Infant, Small for Gestational Age Infant, Very Low Birth Weight Linear Models Magnetic Resonance Imaging / methods Male Psychomotor Performance / physiology Reproducibility of Results Ultrasonography, Doppler, Transcranial / methods |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Structural, immunocytochemical, and mr imaging properties of periventricular crossroads of growing c...
Next Document: Qualitative assessment of brain anomalies in adolescents with mental retardation.