Document Detail

Growth and nutrition after discharge.
MedLine Citation:
PMID:  15001153     Owner:  NLM     Status:  MEDLINE    
Preterm infants are frequently discharged from hospital growth retarded and show reduced growth during childhood. However, nutrition during the post-discharge period has been neglected. Randomized trials show growth benefits, particularly in boys, when nutrient-enriched diets (preterm formula or post-discharge formula) rather than term formula are fed after discharge, with effects persisting beyond the intervention period. These findings suggest that post-discharge period may be a critical time for influencing the growth trajectory, but further research is required to investigate longer-term effects on growth, health and development. Preterm infants who are breast-fed after discharge show slower weight and length gain and lower bone mass than formula-fed infants. Further studies should establish whether differences persist or have long-term consequences, and clarify whether such infants would benefit from post-discharge nutritional supplementation. The introduction of solids may have a significant effect on growth and nutritional status, but insufficient data are currently available for evidence-based guidelines.
Mary S Fewtrell
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Seminars in neonatology : SN     Volume:  8     ISSN:  1084-2756     ISO Abbreviation:  Semin Neonatol     Publication Date:  2003 Apr 
Date Detail:
Created Date:  2004-03-05     Completed Date:  2004-04-02     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  9606001     Medline TA:  Semin Neonatol     Country:  England    
Other Details:
Languages:  eng     Pagination:  169-76     Citation Subset:  IM    
MRC Childhood Nutrition Research Centre, Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK.
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MeSH Terms
Child Development*
Food, Fortified / standards
Growth Disorders / etiology,  prevention & control*
Infant Formula / standards
Infant Nutritional Physiological Phenomena*
Infant, Newborn
Infant, Premature / growth & development*
Infant, Small for Gestational Age / growth & development
Infant, Very Low Birth Weight / growth & development
Nutritional Requirements
Randomized Controlled Trials as Topic
Risk Factors
Sex Factors
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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