Document Detail

Growth hormone treatment in children with Noonan's syndrome: four year results of a partly controlled trial.
MedLine Citation:
PMID:  11529537     Owner:  NLM     Status:  MEDLINE    
CONCLUSION: This study confirmed the gain in H-SDS CA in Noonan's syndrome during long-term GH treatment. However, the accelerating effect of GH on bone maturation seemed to compromise the final height prognosis.
C Noordam; I Van der Burgt; R C Sengers; H A Delemarre-van de Waal; B J Otten
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Publication Detail:
Type:  Clinical Trial; Journal Article; Multicenter Study; Randomized Controlled Trial    
Journal Detail:
Title:  Acta paediatrica (Oslo, Norway : 1992)     Volume:  90     ISSN:  0803-5253     ISO Abbreviation:  Acta Paediatr.     Publication Date:  2001 Aug 
Date Detail:
Created Date:  2001-08-31     Completed Date:  2002-01-03     Revised Date:  2013-05-20    
Medline Journal Info:
Nlm Unique ID:  9205968     Medline TA:  Acta Paediatr     Country:  Norway    
Other Details:
Languages:  eng     Pagination:  889-94     Citation Subset:  IM    
Department of Paediatric Endocrinology, University Medical Centre St Radboud, Nijmegen, The Netherlands.
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MeSH Terms
Analysis of Variance
Body Height / drug effects*
Child, Preschool
Growth Hormone / therapeutic use*
Noonan Syndrome / drug therapy*
Prospective Studies
Time Factors
Reg. No./Substance:
9002-72-6/Growth Hormone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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