| Growth hormone secretion in empty sella syndrome. | |
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MedLine Citation:
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PMID: 6763056 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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GH secretion was studied in 47 patients with empty sella syndrome (ESS), using the GH response to the L-dopa test and determinations of the somatomedin levels. A high frequency of low responders (56%) was found, which is in accordance with previous reports on ESS. However, a true GH deficiency as judged by low levels of somatomedin A, was suspected in only 2 out of 41 patients with otherwise normal pituitary function and in 5 out of 6 patients with other pituitary insufficiences. The impaired GH responsiveness in the remaining patients seemed to be attributed to their overweight and/or postmenopausal age (estrogen deficiency) and not to a true GH deficiency, which was excluded by normal levels of somatomedin. |
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Authors:
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K Brismar |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of endocrinological investigation Volume: 5 ISSN: 0391-4097 ISO Abbreviation: J. Endocrinol. Invest. Publication Date: 1982 Nov-Dec |
Date Detail:
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Created Date: 1983-06-10 Completed Date: 1983-06-10 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7806594 Medline TA: J Endocrinol Invest Country: ITALY |
Other Details:
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Languages: eng Pagination: 417-22 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Empty Sella Syndrome / physiopathology* Female Growth Hormone / deficiency, secretion* Humans Hypoglycemia / chemically induced, physiopathology Insulin / pharmacology Insulin-Like Growth Factor II* Levodopa / pharmacology Male Middle Aged Somatomedins / blood |
| Chemical | |
Reg. No./Substance:
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0/Levodopa; 0/Somatomedins; 11061-68-0/Insulin; 67763-97-7/Insulin-Like Growth Factor II; 9002-72-6/Growth Hormone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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