Document Detail

Growth hormone deficiency in adults--an indication for therapy?
MedLine Citation:
PMID:  3111169     Owner:  NLM     Status:  MEDLINE    
Case studies are presented for two patients, one with isolated hGH deficiency and one with multiple hormone deficiencies. The patients were studied 3 months before, and 3 and 9 months after discontinuing hGH therapy, at 19 and 18 years of age, respectively. Strength in the quadriceps femoris, cross-sectional area of the quadriceps muscles and cross-sectional muscle fibre area were measured. In the patient with multiple hormone deficiencies, clear decreases in all three parameters were evident after discontinuing hGH treatment. There were no significant changes in the other patient. Reasons for these differences are discussed.
M A Preece; J M Round; D A Jones
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Acta paediatrica Scandinavica. Supplement     Volume:  331     ISSN:  0300-8843     ISO Abbreviation:  Acta Paediatr Scand Suppl     Publication Date:  1987  
Date Detail:
Created Date:  1987-07-27     Completed Date:  1987-07-27     Revised Date:  2008-02-20    
Medline Journal Info:
Nlm Unique ID:  0173166     Medline TA:  Acta Paediatr Scand Suppl     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  76-9     Citation Subset:  IM    
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MeSH Terms
Gonadotropin-Releasing Hormone / deficiency
Growth Hormone / deficiency,  therapeutic use*
Muscles / pathology,  physiopathology
Thyrotropin-Releasing Hormone / deficiency
Reg. No./Substance:
24305-27-9/Thyrotropin-Releasing Hormone; 33515-09-2/Gonadotropin-Releasing Hormone; 9002-72-6/Growth Hormone

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