Document Detail

Growth factor therapy to improve soft tissue healing.
MedLine Citation:
PMID:  11823932     Owner:  NLM     Status:  MEDLINE    
The advent of new U.S. Food and Drug Administration-approved products containing growth factors to improve soft tissue healing signifies a new era for wound healing. Over the last decade, some clinical growth factor studies have been promising, whereas others have not shown any positive effect. What many of these studies have shown is that the state of a healing wound is not only dependent on its growth factor milieu but also on other variables (wound care, tissue oxygen state, bacteria count, and nutritional status of the patient). This article describes recent progress with growth factors on soft tissue structures (skin, mucosa, and nerve) relevant to the facial plastic and reconstructive surgeon.
David B Hom; Gentry Thatcher; Robert Tibesar
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.; Review    
Journal Detail:
Title:  Facial plastic surgery : FPS     Volume:  18     ISSN:  0736-6825     ISO Abbreviation:  Facial Plast Surg     Publication Date:  2002 Feb 
Date Detail:
Created Date:  2002-02-01     Completed Date:  2002-06-04     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  8405303     Medline TA:  Facial Plast Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  41-52     Citation Subset:  D    
Division of Facial Plastic and Reconstructive Surgery, Department of Otolaryngology-Head and Neck Surgery, University of Minnesota School of Medicine and Hennepin County Medical Center, Minneapolis, MN 55455, USA.
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MeSH Terms
Growth Substances / pharmacology*,  therapeutic use*
Mucous Membrane / injuries
Peripheral Nerves / injuries
Reconstructive Surgical Procedures*
Skin / injuries
Soft Tissue Injuries / therapy*
Wound Healing / drug effects*
Grant Support
Reg. No./Substance:
0/Growth Substances

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