| Growth factor regulation of cell cycle progression in mammary epithelial cells. | |
| | |
MedLine Citation:
|
PMID: 15082915 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Growth factors are among the critical positive and negative regulators of cell proliferation for normal mammary/breast epithelial cells and for breast cancer cells. The mechanisms by which specific growth factors regulate the cell cycle in mammary/breast epithelial cells is beginning to be understood for several growth factor families, including the epidermal growth factor, insulin-like growth factor, and transforming growth factor-beta families. A critical issue for understanding how growth factors regulate the cell cycle in vivo is how individual factors interact with other growth factors or hormones to enhance or inhibit specific molecular targets in the cell cycle machinery. This review addresses what is currently known about how growth factors regulate the cell cycle in mammary/breast epithelial cells both individually and in coordination with other growth regulators. |
| | |
Authors:
|
Malinda A Stull; Anne M Rowzee; Aimee V Loladze; Teresa L Wood |
Related Documents
:
|
7737795 - Chondrocyte differentiation. 21294645 - Thyrotropin receptor and membrane interactions in frtl-5 thyroid cell strain in microgr... 6528125 - Cellular oncogenes, growth factors, and cellular growth control. 10564275 - Uptake and intracellular transport of acidic fibroblast growth factor: evidence for fre... 2497425 - Evidence that stimulation of growth following long term density arrest of wi-38 cells p... 8006075 - Study of the higher eukaryotic gene function cdk2 using fission yeast. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.; Review |
Journal Detail:
|
Title: Journal of mammary gland biology and neoplasia Volume: 9 ISSN: 1083-3021 ISO Abbreviation: J Mammary Gland Biol Neoplasia Publication Date: 2004 Jan |
Date Detail:
|
Created Date: 2004-04-14 Completed Date: 2004-12-07 Revised Date: 2007-11-14 |
Medline Journal Info:
|
Nlm Unique ID: 9601804 Medline TA: J Mammary Gland Biol Neoplasia Country: United States |
Other Details:
|
Languages: eng Pagination: 15-26 Citation Subset: IM |
Affiliation:
|
Department of Neural and Behavioral Sciences, Penn State College of Medicine, Hershey, Pennsylvania 17033, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Breast Neoplasms
/
physiopathology* Cell Cycle / physiology* Cell Proliferation* Epithelial Cells / physiology Female Growth Substances / pharmacology* Humans Mammary Glands, Human / physiology* |
| Grant Support | |
ID/Acronym/Agency:
|
CA83174/CA/NCI NIH HHS |
| Chemical | |
Reg. No./Substance:
|
0/Growth Substances |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Steroid receptors and cell cycle in normal mammary epithelium.
Next Document: Of mice and Myc: c-Myc and mammary tumorigenesis.