| Growth differences of male and female Göttingen minipigs during ad libitum feeding: a pilot study. | |
| | |
MedLine Citation:
|
PMID: 15703128 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Even though minipigs have been used in biomedical research for nearly half a century now, no specific nutrient requirements are available. For that reason a series of studies into the nutrient requirements of Göttingen minipigs were carried out. Firstly, a pilot study was carried out to determine the ad libitum feed intake (FI) during growth, as a reference for later feed restriction studies. Four male and four female minipigs were fed two types of diet, one standard pig diet (20.6% crude protein; 11.7% crude fat; 13.5 mJ/kg DM metabolizable energy) and one diet specially designed for minipigs (12.0% crude protein; 2.9% crude fat; 11.9 MJ/kg DM metabolizable energy). When fed ad libitum for 13 weeks, female Göttingen minipigs developed a significantly (P<0.05) higher body weight (BW) than males (27.4 vs 16.6 kg) on either diet. The large difference in growth between male and female Göttingen minipigs did not appear to be the result from differences in metabolizable energy intake. Metabolizable energy intake of male and female Göttingen minipigs could be predicted by ME=1877 kJxBW(0.61). Both male and female Göttingen minipigs became obese when fed ad libitum, defined by relative backfat thickness. Relative backfat thickness ranged from 5 to 13 cm/100 kg. Females had thicker relative backfat layers than males. Remarkably, no large changes in haematology and clinical chemistry occurred in ad libitum fed Göttingen minipigs as compared to reference values, and no abnormalities other than enlarged fat reserves were observed at necropsy. Apparently, Göttingen minipigs do not restrain FI voluntarily, and restricted feeding is therefore indicated to prevent obesity. |
| | |
Authors:
|
P J A Bollen; L W Madsen; O Meyer; J Ritskes-Hoitinga |
Related Documents
:
|
6673988 - Differential effects of dietary caloric and protein restriction in the aging rat. 10708248 - Metabolic mass, metabolic rate, caloric restriction, and aging in male fischer 344 rats. 402808 - Protein and calorie malnutrition in infant cebus monkeys: growth and behavioral develop... 7884828 - Effects of a daily feeding-restriction on the reproductive and development toxicity par... 14511148 - Teratogenic effects of chronic ingestion of high levels of vitamin a in cats. 11432768 - Inter-pregnancy folate and iron status of women in an inner-city population. |
Publication Detail:
|
Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Laboratory animals Volume: 39 ISSN: 0023-6772 ISO Abbreviation: Lab. Anim. Publication Date: 2005 Jan |
Date Detail:
|
Created Date: 2005-02-10 Completed Date: 2005-03-17 Revised Date: 2008-11-21 |
Medline Journal Info:
|
Nlm Unique ID: 0112725 Medline TA: Lab Anim Country: England |
Other Details:
|
Languages: eng Pagination: 80-93 Citation Subset: IM |
Affiliation:
|
Biomedical Laboratory, University of Southern Denmark, Winsloewparken 23, DK-5000 Odense C, Denmark. pbollen@health.sdu.dk |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aging Animal Nutritional Physiological Phenomena Animals Diet* Dietary Fats / administration & dosage Dietary Proteins / administration & dosage Energy Intake Female Male Pilot Projects Sex Characteristics* Swine / growth & development* Swine, Miniature / growth & development* Weight Gain |
| Chemical | |
Reg. No./Substance:
|
0/Dietary Fats; 0/Dietary Proteins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Interpretation of two-stage experiments in animal studies.
Next Document: Description of a technique for anaesthetizing pregnant ewes for fetal surgery.