Document Detail

Growth curve of ruptured aortic aneurysm.
MedLine Citation:
PMID:  9537528     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: We hypothesized that the aortic aneurysm might grow biexponentially. The object of this study was to determine the biexponential growth curve of aortic aneurysm. DESIGN: A fifteen-year retrospective review of CT images of aortic aneurysm. SETTING: Major cardiovascular referral center. PATIENTS: Patients with true aortic aneurysm who were followed up with CT and performed CT at their aneurysmal ruptures. MEASURES: The largest short-axial diameters of the outer contour of the aneurysms were measured. Aortic aneurysmal diameters were normalized by those at ruptures, and the plots were fitted to the biexponential curve. RESULTS: Eight patients out of 1481 had been followed up with CT scans. In regression analysis, the values fit well to the biexponential equation: d(t) = 0.8345 exp (0.0052 t) + 0.1653 exp (0.8275 t), r = 0.934 where d(t) is the normalized diameter, and t is months before rupture. The first part of the equation mainly expresses the slow growth, and the second expresses the rapid growth shortly before rupture. CONCLUSIONS: Aortic aneurysm began to grow faster at about three months before rupture. It is important to find out the point that the growth of aortic aneurysm changes its rate faster than before, and once the point is observed, elective repair should be considered.
Y Hirose; M Takamiya
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of cardiovascular surgery     Volume:  39     ISSN:  0021-9509     ISO Abbreviation:  J Cardiovasc Surg (Torino)     Publication Date:  1998 Feb 
Date Detail:
Created Date:  1998-04-21     Completed Date:  1998-04-21     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0066127     Medline TA:  J Cardiovasc Surg (Torino)     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  9-13     Citation Subset:  IM    
Department of Radiology, National Cardiovascular Center, Osaka, Japan.
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MeSH Terms
Aortic Aneurysm, Abdominal / epidemiology,  radiography*
Aortic Aneurysm, Thoracic / epidemiology,  radiography*
Aortic Rupture / epidemiology,  radiography*
Follow-Up Studies
Regression Analysis
Retrospective Studies
Risk Factors
Time Factors
Tomography, X-Ray Computed

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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