Document Detail

Growth conditions regulate the requirements for Caulobacter chromosome segregation.
MedLine Citation:
PMID:  19028887     Owner:  NLM     Status:  MEDLINE    
Growth environments are important metabolic and developmental regulators. Here we demonstrate a growth environment-dependent effect on Caulobacter chromosome segregation of a small-molecule inhibitor of the MreB bacterial actin cytoskeleton. Our results also implicate ParAB as important segregation determinants, suggesting that multiple distinct mechanisms can mediate Caulobacter chromosome segregation and that their relative contributions can be environmentally regulated.
Conrad W Shebelut; Rasmus B Jensen; Zemer Gitai
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.     Date:  2008-11-21
Journal Detail:
Title:  Journal of bacteriology     Volume:  191     ISSN:  1098-5530     ISO Abbreviation:  J. Bacteriol.     Publication Date:  2009 Feb 
Date Detail:
Created Date:  2009-01-19     Completed Date:  2009-04-02     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  2985120R     Medline TA:  J Bacteriol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1097-100     Citation Subset:  IM    
Department of Molecular Biology, Princeton University, Washington Rd., Princeton, NJ 08544, USA.
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MeSH Terms
Bacterial Proteins / genetics,  physiology
Caulobacter / drug effects,  genetics*
Chromosome Segregation / drug effects,  genetics*
Chromosomes, Bacterial / genetics*
Thiourea / analogs & derivatives,  pharmacology
Reg. No./Substance:
0/Bacterial Proteins; 27806-81-1/2,6-dichlorobenzylthiopseudourea; 62-56-6/Thiourea

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