Document Detail

Growth and bone mineralization in preterm infants fed preterm formula or standard term formula after discharge.
MedLine Citation:
PMID:  18657828     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To evaluate growth and bone mineralization in very low birth weight (VLBW) infants fed preterm formula (PF) or term formula (TF). STUDY DESIGN: In a double-blind prospective study, 49 preterm infants of gestational age 33 weeks or less were randomly fed PF or TF for 2 months after discharge, then all of the infants were fed TF for the next 2 months. Anthropometric and dual-energy x-ray absorptiometry data were collected at discharge and at 2 months and 4 months after discharge. Anthropometric data also were collected at 12 months postterm. RESULTS: Four months after discharge, both body weight (6139 +/- 1254 g vs 5540 +/- 863 g; P = .03) and bone mineral content (104.4 +/- 29.2 g vs 87.5 +/- 17.1 g; P = .01) were significantly higher in the PF group compared with the TF group. At 12 months postterm, mean body weight, length, and head circumference remained higher in the PF group than in the TF group, and body mass index was similar and within the normal range in the 2 groups. CONCLUSIONS: At 4 months after discharge, growth and mineralization were better in the VLBW infants who were fed PF during the first 2 months after discharge compared with those who were fed TF, suggesting that PF may be particularly valuable at this early stage of development.
Jean-Charles Picaud; Evelyne Decullier; Odile Plan; Odile Pidoux; Sylvie Bin-Dorel; Louis-Dominique van Egroo; Francois Chapuis; Olivier Claris
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Publication Detail:
Type:  Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't     Date:  2008-07-26
Journal Detail:
Title:  The Journal of pediatrics     Volume:  153     ISSN:  1097-6833     ISO Abbreviation:  J. Pediatr.     Publication Date:  2008 Nov 
Date Detail:
Created Date:  2008-10-22     Completed Date:  2008-11-10     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0375410     Medline TA:  J Pediatr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  616-21, 621.e1-2     Citation Subset:  AIM; IM    
CHU de Montpellier, Service de Neonatologie, Hopital Arnaud de Villeneuve, Université de Montpellier, Montpellier, France.
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MeSH Terms
Body Weight
Bone Density
Calcification, Physiologic*
Double-Blind Method
Gestational Age
Infant Formula*
Infant Nutritional Physiological Phenomena
Infant, Newborn
Infant, Premature / growth & development
Prospective Studies
Weight Gain

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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