Document Detail


Growth and survival of zebrafish (Danio rerio) fed different commercial and laboratory diets.
MedLine Citation:
PMID:  19566408     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The need to develop standardized diets to support zebrafish (Danio rerio) research is supported by the knowledge that specific dietary ingredients, nutrients, or antinutritional factors in diets have been shown to affect development and growth of adult D. rerio and their offspring. In this study, there were seven dietary treatments consisting of five commercially available diets and two laboratory-prepared diets, three replicates per treatment. Fish were fed ad libitum twice daily for 9 weeks. At 9 weeks, both weight and length were recorded to determine condition indices. D. rerio fed one of the laboratory-prepared diets had significantly higher weights than individuals fed any of the other diets and exhibited significantly higher lengths than those fed five of the six remaining diets. Although there were significant differences in general growth demographics (length/weight) after the 9-week feeding trial, no significant differences in overall health of D. rerio were observed for the different dietary treatments as determined by statistical analysis of condition factor indices (K = [weight x 100]/length(3)). The success achieved with the laboratory-prepared diets represents the foundation for establishing an open-formulation nutritional standard to ensure that the D. rerio model for research does not generate confounding research results caused by nutritional vagaries.
Authors:
Anthony J Siccardi; Heath W Garris; Warren T Jones; Dorothy B Moseley; Louis R D'Abramo; Stephen A Watts
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural    
Journal Detail:
Title:  Zebrafish     Volume:  6     ISSN:  1557-8542     ISO Abbreviation:  Zebrafish     Publication Date:  2009 Sep 
Date Detail:
Created Date:  2009-09-18     Completed Date:  2009-11-03     Revised Date:  2011-08-25    
Medline Journal Info:
Nlm Unique ID:  101225070     Medline TA:  Zebrafish     Country:  United States    
Other Details:
Languages:  eng     Pagination:  275-80     Citation Subset:  IM    
Affiliation:
Department of Biology, University of Alabama at Birmingham, Birmingham, Alabama 35295-1170, USA. asiccardi15@aol.com
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MeSH Terms
Descriptor/Qualifier:
Animals
Biometry
Body Weight
Diet*
Survival Rate
Zebrafish / anatomy & histology,  growth & development*
Grant Support
ID/Acronym/Agency:
P30AR046031/AR/NIAMS NIH HHS
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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