Document Detail

Grown-up Kawasaki disease patients who have giant coronary aneurysms.
MedLine Citation:
PMID:  20143209     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Many Kawasaki disease (KD) patients have reached adulthood in Japan. The current status of adult patients who have giant coronary aneurysms with KD is not well understood. METHODS: Medical records of 48 KD patients (33 males and 15 females) with giant coronary aneurysms (maximum coronary artery internal diameter >8 mm) aged 20 years or over were retrospectively reviewed. RESULTS: The age of the patients at the diagnosis of KD ranged from 0.3 to 12.8 years (median 2.9 years) and the age of the patients in this review ranged from 20.0 to 33.1 years (median 25.2 years). During the follow-up period, the maximum coronary artery internal diameter ranged from 8.2 to 30.0 mm (median 10 mm). Giant coronary aneurysms progressed to coronary artery stenosis and/or complete occlusion in 34 (74%) of 46 patients. Coronary artery bypass graft surgery was performed in 9 (19%) of 48 patients. Myocardial infarction occurred in 14 (31%) of 45 patients. Other complications or problems occurred in 5 patients with angina pectoris, low left ventricular ejection fraction, ventricular tachycardia, hemorrhagic cerebral infarction, or thyroid carcinoma respectively. In the patients followed up, 4 dropped out. In addition, 1 patient succeeded in pregnancy and delivered a baby. CONCLUSIONS: Close attention should be paid to ventricular tachycardia in adult KD patients with giant coronary aneurysms, especially for those who have low left ventricular ejection fraction. To reduce the number of dropped out patients, it is important that the patients should be referred to a new doctor when they change their place of residence.
Kazunori Samada; Hirohiko Shiraishi; Asami Sato; Mariko Y Momoi
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-02-09
Journal Detail:
Title:  World journal of pediatrics : WJP     Volume:  6     ISSN:  1867-0687     ISO Abbreviation:  World J Pediatr     Publication Date:  2010 Feb 
Date Detail:
Created Date:  2010-02-09     Completed Date:  2010-07-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101278599     Medline TA:  World J Pediatr     Country:  China    
Other Details:
Languages:  eng     Pagination:  38-42     Citation Subset:  IM    
Department of Pediatrics, Jichi Medical University, Tochigi, 329-0498, Japan.
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MeSH Terms
Angina Pectoris / epidemiology
Brain Infarction / epidemiology
Coronary Aneurysm / epidemiology*
Coronary Artery Bypass / statistics & numerical data
Coronary Occlusion / epidemiology
Coronary Stenosis / epidemiology
Follow-Up Studies
Japan / epidemiology
Mucocutaneous Lymph Node Syndrome / epidemiology*
Myocardial Infarction / epidemiology
Retrospective Studies
Stroke Volume
Tachycardia, Ventricular / epidemiology
Thyroid Neoplasms / epidemiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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