Document Detail


Group A streptococcus-associated upper respiratory tract infections in a day-care center.
MedLine Citation:
PMID:  2645567     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Little information is available about the epidemiology of group A streptococcal upper respiratory tract infections in child day-care centers. During an initial 3-month period, symptomatic upper respiratory tract infections associated with throat cultures or rapid antigen detection tests positive for group A streptococci developed in 55 of 214 (26%) children and adult staff in one day-care center. When the entire day-care center population (except for those receiving antibiotics at the time) was then surveyed, 52 of 146 (36%) children and two of 24 (8%) adult staff had throat cultures positive for group A streptococci. Of the 54 group A streptococcal isolates found during the survey, the three most frequently encountered serotypes were M2,T2/28 (35%), M3,T3/13 (30%), and M-NT, T25 (20%). Rapid antigen detection was performed at the same time as the throat culture in the first 98 individuals examined during the culture survey but was positive in only 11 (35%) of 31 individuals with positive throat cultures. Sensitivity of the rapid antigen test was related to degree of positivity of the throat culture but not to age. The overall group A streptococcal positivity rate was 49% for 187 children and 33% for 27 adult staff; 18 of 66 (27%) children younger than 31/2 years of age were found to have group A streptococci in their upper respiratory tracts. This is the first report of high prevalence rates of group A streptococci associated with upper respiratory tract infections in a day-care center. The group A Streptococcus may represent a significant upper respiratory tract pathogen in the day-care setting.
Authors:
T D Smith; V Wilkinson; E L Kaplan
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Pediatrics     Volume:  83     ISSN:  0031-4005     ISO Abbreviation:  Pediatrics     Publication Date:  1989 Mar 
Date Detail:
Created Date:  1989-04-03     Completed Date:  1989-04-03     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0376422     Medline TA:  Pediatrics     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  380-4     Citation Subset:  AIM; IM    
Affiliation:
Department of Pediatrics, University of Minnesota Medical School, Minneapolis, MN 55455.
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MeSH Terms
Descriptor/Qualifier:
Adult
Antigens, Bacterial / analysis
Bacteriological Techniques
Carrier State / microbiology
Child
Child Day Care Centers*
Child, Preschool
Disease Outbreaks*
Humans
Infant
Pharyngitis / epidemiology
Respiratory Tract Infections / epidemiology*,  microbiology
Serotyping
Streptococcal Infections / epidemiology*,  microbiology
Streptococcus pyogenes / immunology,  isolation & purification
Chemical
Reg. No./Substance:
0/Antigens, Bacterial

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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