Document Detail

Group housing accelerates growth and induces obesity in adult hamsters.
MedLine Citation:
PMID:  3394835     Owner:  NLM     Status:  MEDLINE    
To determine whether variable body heat loss may influence control of growth and regulation of body fat content in hamsters, mature female hamsters were housed for 7-14 wk in one of three conditions: individually in metal cages (n = 6), individually in plastic boxes with bedding (n = 6), or communally (6 per box) in plastic boxes with bedding. Their resting metabolic rate (RMR) was measured individually or in pairs of two between days 65 and 75. When thermal properties of shelter varied alone, singly housed hamsters regulated energy balance fairly accurately by compensatory changes in food intake, and their rate of growth was unaffected. In contrast, group housing induced acceleration of growth and obesity without hyperphagia, was associated with an acute inhibition of RMR in hamsters tested in pairs, and was associated with a chronic inhibition of RMR in hamsters tested individually. We conclude that conspecific body contact in mature group-housed hamsters accelerates somatic growth and increases fat deposition. Energy for this anabolism is derived, in part, from reduced RMR and, in part, from a slight increase in food consumption.
K T Borer; A Pryor; C A Conn; R Bonna; M Kielb
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  The American journal of physiology     Volume:  255     ISSN:  0002-9513     ISO Abbreviation:  Am. J. Physiol.     Publication Date:  1988 Jul 
Date Detail:
Created Date:  1988-08-12     Completed Date:  1988-08-12     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370511     Medline TA:  Am J Physiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  R128-33     Citation Subset:  IM    
Department of Kinesiology, University of Michigan, Ann Arbor 48109.
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MeSH Terms
Adipose Tissue / anatomy & histology
Basal Metabolism
Body Temperature Regulation
Fatty Acid Synthetase Complex / metabolism
Housing, Animal*
Liver / enzymology
Malate Dehydrogenase / metabolism
Reg. No./Substance:
EC Dehydrogenase; EC 6.-/Fatty Acid Synthetase Complex

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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