Document Detail


Group B streptococcal necrotizing fasciitis and streptococcal toxic shock-like syndrome in adults.
MedLine Citation:
PMID:  9701105     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Necrotizing fasciitis, which is a severe and uncommon infection involving the subcutaneous tissues, is usually caused by group A streptococci. To our knowledge, however, group B streptococci (Streptococcus agalactiae) have been reported to cause necrotizing fasciitis in only 4 instances (2 involving neonates) over the past 4 decades. We report 3 cases of group B streptococcal necrotizing fasciitis in adults that occurred in southern Ontario and Quebec within a 10-month period. All 3 patients had significant underlying illness, and all required surgical debridement in addition to antibiotic therapy. One of the cases fulfilled the criteria for streptococcal toxic shock-like syndrome. Group B streptococcus has been recognized as a frequent cause of serious disease in adults. It has become evident over the past decade that invasive streptococcal infections are on the increase. We speculate that group B streptococcus has recently acquired an increased ability to cause necrotizing fasciitis and suggest that this may represent the emergence of a new clinical syndrome in adults.
Authors:
M A Gardam; D E Low; R Saginur; M A Miller
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Archives of internal medicine     Volume:  158     ISSN:  0003-9926     ISO Abbreviation:  Arch. Intern. Med.     Publication Date:    1998 Aug 10-24
Date Detail:
Created Date:  1998-09-03     Completed Date:  1998-09-03     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0372440     Medline TA:  Arch Intern Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1704-8     Citation Subset:  AIM; IM    
Affiliation:
Department of Microbiology, Sir Mortimer B. Davis-Jewish General Hospital, McGill University, Montreal, Quebec, Canada.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Fasciitis, Necrotizing / epidemiology*,  therapy
Female
Humans
Male
Middle Aged
Ontario / epidemiology
Quebec / epidemiology
Shock, Septic / epidemiology,  microbiology*
Streptococcus agalactiae / isolation & purification*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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