Document Detail

Group B streptococcal meningitis in adults: recent increase in Southeast Asia.
MedLine Citation:
PMID:  10985511     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Meningitis caused by Streptococcus agalactiae (Group B Streptococcus) is rare in adults and usually affects patients with predisposing conditions. AIMS: To describe an increase in adult group B streptococcal meningitis occurring in parallel in Hong Kong and Singapore. METHODS: All cases of bacterial meningitis admitted to the Prince of Wales Hospital, Hong Kong and Singapore General Hospital in 1998, aged 15 years or above, were reviewed. Medical records for the previous ten years were searched for previous cases of adult group B streptococcal meningitis. RESULTS: In 1998, 29 adult patients with bacterial meningitis were admitted to the two hospitals. S. agalactiae was isolated in 11 cases, Streptococcus pneumoniae in three cases, Klebsiella pneumoniae in two cases, and Pseudomonas pseudomallei in one case. In 11 cases no bacteriological diagnosis could be made. Two patients with adult group B streptococcal meningitis had predisposing conditions for infection. One patient died before a definite diagnosis could be established. A ten year review of records revealed one previous case of adult group B streptococcal meningitis in a patient with multiple risk factors. CONCLUSIONS: An increase of group B streptococcal meningitis has occurred among adults admitted to two major hospitals in two Southeast Asian cities. In the majority of cases there were no identifiable predisposing conditions. The cause of this increase of group B streptococcal remains unclear.
E Wilder-Smith; K M Chow; R Kay; M Ip; N Tee
Publication Detail:
Type:  Journal Article; Multicenter Study    
Journal Detail:
Title:  Australian and New Zealand journal of medicine     Volume:  30     ISSN:  0004-8291     ISO Abbreviation:  Aust N Z J Med     Publication Date:  2000 Aug 
Date Detail:
Created Date:  2000-12-18     Completed Date:  2001-01-11     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  1264322     Medline TA:  Aust N Z J Med     Country:  AUSTRALIA    
Other Details:
Languages:  eng     Pagination:  462-5     Citation Subset:  IM    
Department of Neurology, Singapore General Hospital, Singapore.
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MeSH Terms
Hong Kong / epidemiology
Meningitis, Bacterial / epidemiology*
Middle Aged
Singapore / epidemiology
Streptococcal Infections / epidemiology*
Streptococcus agalactiae*

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