Document Detail

Group B streptococcal disease in the perinatal period.
MedLine Citation:
PMID:  8304264     Owner:  NLM     Status:  MEDLINE    
Group B streptococcus is the major cause of neonatal sepsis in the United States. It is estimated that 2,000 infants die annually of syndromes related to group B streptococcus infection. In the early-onset syndrome, transmission is from mother to child, either in utero or during birth. Pneumonia is the most common presentation in infants who develop symptoms during the first seven days of life. The principal manifestation of late-onset infection is meningitis, which occurs in 85 percent of this group. Although group B streptococcus infection is normally remediable with penicillin therapy, rapid diagnosis and treatment are necessary to prevent the serious consequences of the disease. A vaccine is under development, although the cost-effectiveness of a widespread immunization program for a disease with such a low frequency is still unknown. The potentially serious outcomes of this infection, however, make it a major problem for physicians involved in neonatal care.
M W Platt; G J Gilson
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  American family physician     Volume:  49     ISSN:  0002-838X     ISO Abbreviation:  Am Fam Physician     Publication Date:  1994 Feb 
Date Detail:
Created Date:  1994-03-04     Completed Date:  1994-03-04     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  1272646     Medline TA:  Am Fam Physician     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  434-42     Citation Subset:  AIM; IM    
Department of Microbiology, University of New Mexico School of Medicine, Albuquerque.
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MeSH Terms
Infant, Newborn
Streptococcal Infections* / diagnosis,  drug therapy,  epidemiology
Streptococcus agalactiae*
Time Factors
United States / epidemiology
Comment In:
Am Fam Physician. 1994 Feb 1;49(2):315-6, 318   [PMID:  8304252 ]
Am Fam Physician. 1994 Aug;50(2):304, 306   [PMID:  8042564 ]
Erratum In:
Am Fam Physician 1994 Nov 15;50(7):1471

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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