Document Detail

Gross and microscopic findings in patients undergoing microdermabrasion for facial rejuvenation.
MedLine Citation:
PMID:  11442614     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Microdermabrasion (MDA) is a new procedure used for the treatment of cosmetic problems, particularly to combat photoaging and intrinsic aging. Though excellent clinical improvement has been well documented, histologic support is limited. OBJECTIVE: To determine if microscopic changes correlate with clinical improvement and to examine the depth of penetration compared to chemical peels. METHODS: Seven women were submitted to five MDA sessions at weekly intervals. Skin biopsies were performed in all of them, before and after the treatment. Clinical and photographic assessments were recorded weekly. Data concerning skin features, including oiliness, thickness, dilated pores, and general appearance, were all assessed. Microscopic improvement of changes associated with cutaneous aging in the epidermis and dermis where all assessed. For statistical analysis, a t-test for small samples was utilized. RESULTS: All the patients showed clinical and microscopic improvement in all of the parameters assessed. The t-test for small samples showed a P <.05. CONCLUSION: MDA is a good alternative for facial rejuvenation. Improvements in both clinical and microscopic parameters are readily demonstrable.
E Hernandez-Perez; E V Ibiett
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]     Volume:  27     ISSN:  1076-0512     ISO Abbreviation:  Dermatol Surg     Publication Date:  2001 Jul 
Date Detail:
Created Date:  2001-07-09     Completed Date:  2001-08-02     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9504371     Medline TA:  Dermatol Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  637-40     Citation Subset:  IM    
Center for Dermatology and Cosmetic Surgery, San Salvador, El Salvador.
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MeSH Terms
Middle Aged
Prospective Studies
Skin / pathology*
Skin Aging*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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