Document Detail

Groin tissue necrosis requiring skin graft following parenteral abuse of buprenorphine tablets.
MedLine Citation:
PMID:  15385230     Owner:  NLM     Status:  MEDLINE    
In May 2002 Buprenorphine (Subutex) was listed on the Australian Pharmaceutical Benefits Schedule for treatment in opioid dependence. In addition to broadening treatment options, buprenorphine has the advantage of an improved safety profile. The risk of overdose is lessened but other risks remain due to diversion. French experience reports widespread deviation of buprenorphine sublingual tablets to intravenous injection. We report a case of attempted parenteral administration of buprenorphine tablets. Stringent protocols for dispensing are appropriate.
G F X Feeney; P Fairweather
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Drug and alcohol review     Volume:  22     ISSN:  0959-5236     ISO Abbreviation:  Drug Alcohol Rev     Publication Date:  2003 Sep 
Date Detail:
Created Date:  2004-09-23     Completed Date:  2005-01-11     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9015440     Medline TA:  Drug Alcohol Rev     Country:  England    
Other Details:
Languages:  eng     Pagination:  359-61     Citation Subset:  IM    
Alcohol and Drug Assessment Unit, Princess Alexandra Hospital, Brisbane, Queensland, Australia.
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MeSH Terms
Analgesics, Opioid / administration & dosage,  adverse effects*
Buprenorphine / administration & dosage,  adverse effects*
Groin / pathology*,  surgery*
Necrosis / chemically induced*
Skin Transplantation / methods*
Substance Abuse, Intravenous / complications*
Reg. No./Substance:
0/Analgesics, Opioid; 52485-79-7/Buprenorphine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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