| Griseofulvin therapy of lichen planus. | |
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MedLine Citation:
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PMID: 6177168 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Thirty-one patients who had lichen planus treated with griseofulvin were randomly selected for review from a group of patients with lichen planus seen at the Mayo Clinic between January 1976 and June 1980; two patients were excluded because of lack of adequate follow-up. Of the 11 patients with only oral lesions, 6 showed a marked improvement or complete remission. Of the 18 patients with lichen planus involving one or more sites with or without oral lesions, 15 had cutaneous lesions. Three of the 15 had improvement of their cutaneous lesions; however, 1 of the 3 continued to develop new lesions, although old ones were improving. In patients with recalcitrant, symptomatic oral lichen planus, a trial of griseofulvin would seem justified. Success in patients with cutaneous lichen planus is less likely; however, griseofulvin may afford relief in selected patients. This study indicates that further prospective studies are needed to clarify the efficacy of griseofulvin in lichen planus. |
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Authors:
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M C Massa; R S Rogers |
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Publication Detail:
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Type: Case Reports; Clinical Trial; Journal Article |
Journal Detail:
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Title: Acta dermato-venereologica Volume: 61 ISSN: 0001-5555 ISO Abbreviation: Acta Derm. Venereol. Publication Date: 1981 |
Date Detail:
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Created Date: 1982-07-08 Completed Date: 1982-07-08 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0370310 Medline TA: Acta Derm Venereol Country: SWEDEN |
Other Details:
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Languages: eng Pagination: 547-50 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Clinical Trials as Topic Female Griseofulvin / therapeutic use* Humans Lichen Planus / drug therapy*, pathology Male Middle Aged Mouth Diseases / drug therapy, pathology Retrospective Studies Skin / pathology |
| Chemical | |
Reg. No./Substance:
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126-07-8/Griseofulvin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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