Document Detail


Green tea or rosemary extract added to foods reduces nonheme-iron absorption.
MedLine Citation:
PMID:  11237939     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Phenolic compounds act as food antioxidants. One of the postulated mechanisms of action is chelation of prooxidant metals, such as iron. Although the antioxidative effect is desirable, this mechanism may impair the utilization of dietary iron. OBJECTIVE: We sought to determine the effect of phenolic-rich extracts obtained from green tea or rosemary on nonheme-iron absorption. DESIGN: Young women aged 19-39 y consumed test meals on 4 separate occasions. The meals were identical except for the absence (meal A) or presence (meal B) of a phenolic-rich extract from green tea (study 1; n = 10) or rosemary (study 2; n = 14). The extracts (0.1 mmol) were added to the meat component of the test meals. The meals were extrinsically labeled with either 55Fe or 59Fe and were consumed on 4 consecutive days in the order ABBA or BAAB. Iron absorption was determined by measuring whole-body retention of 59Fe and the ratio of 55Fe to 59Fe activity in blood samples. RESULTS: The presence of the phenolic-rich extracts resulted in decreased nonheme-iron absorption. Mean (+/-SD) iron absorption decreased from 12.1 +/- 4.5% to 8.9 +/- 5.2% (P < 0.01) in the presence of green tea extract and from 7.5 +/- 4.0% to 6.4 +/- 4.7% (P < 0.05) in the presence of rosemary extract. CONCLUSION: Phenolic-rich extracts used as antioxidants in foods reduce the utilization of dietary iron.
Authors:
S Samman; B Sandström; M B Toft; K Bukhave; M Jensen; S S Sørensen; M Hansen
Related Documents :
14704299 - A low-molecular-weight factor in human milk whey promotes iron uptake by caco-2 cells.
11925489 - Commentary: experiences and challenges in industrialized countries.
11815809 - Effects of iron sulfate dosage on the water flea (daphnia magna straus) and early devel...
17722409 - Effect of germination of finger millet on nutritional value of foods and effect of food...
2485579 - Fortification of the diet as a strategy for preventing iron deficiency.
9877539 - Modification of the ferrozine technique to analyze iron contents in different foods: co...
23072219 - The relationship between emotions and food consumption (macronutrient) in a foodservice...
8609169 - Inner dynein arms but not outer dynein arms require the activity of kinesin homologue p...
20373189 - A review of thin layer drying of foods: theory, modeling, and experimental results.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The American journal of clinical nutrition     Volume:  73     ISSN:  0002-9165     ISO Abbreviation:  Am. J. Clin. Nutr.     Publication Date:  2001 Mar 
Date Detail:
Created Date:  2001-03-12     Completed Date:  2001-05-24     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0376027     Medline TA:  Am J Clin Nutr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  607-12     Citation Subset:  AIM; IM    
Affiliation:
Research Department of Human Nutrition, LMC Centre for Advanced Food Studies, The Royal Veterinary and Agricultural University, Frederiksberg, Denmark. s.samman@biochem.usyd.edu.au
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Biological Availability
Female
Humans
Intestinal Absorption / drug effects*
Iron / blood*
Iron Chelating Agents / adverse effects
Iron Isotopes / blood,  diagnostic use
Iron, Dietary / administration & dosage,  pharmacokinetics*
Lamiaceae / adverse effects*,  chemistry
Plant Extracts / administration & dosage,  adverse effects
Tea / adverse effects*,  chemistry
Chemical
Reg. No./Substance:
0/Iron Chelating Agents; 0/Iron Isotopes; 0/Iron, Dietary; 0/Plant Extracts; 0/Tea; 7439-89-6/Iron

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Diminished and erratic absorption of ergocalciferol in adult cystic fibrosis patients.
Next Document:  Determinants of plasma total homocysteine concentration in the Framingham Offspring cohort.