Document Detail


Greater coffee intake in men is associated with steeper age-related increases in blood pressure.
MedLine Citation:
PMID:  21088672     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Administration of caffeine or caffeinated coffee in laboratory and ambulatory settings results in small to moderate acute increases in blood pressure (BP). However, habitual coffee intake has not been linked conclusively to long-term increases in basal BP, and findings are inconsistent by sex. This study examined longitudinal relations of habitual coffee use to resting BP and pulse pressure.
METHODS: In a sample of 2,442 participants from the Baltimore Longitudinal Study of Aging (BLSA), coffee consumption was used to predict resting systolic and diastolic BP and pulse pressure using longitudinal mixed-effects regression models adjusted for age, education, antihypertensive, and antihyperlipidemic use, smoking, and body mass index (BMI). Analyses were stratified by sex (865 women and 1,577 men), and age and BMI were examined as possible effect modifiers.
RESULTS: In men, we identified a significant three-way interaction among coffee intake (nonlinear), baseline age, and length of follow-up for systolic BP (SBP) and pulse pressure. A significant interaction of coffee intake and BMI (nonlinear) was also noted for SBP in men. There were no significant relations of coffee intake to BP or pulse pressure in women.
CONCLUSION: Greater coffee intake in men was associated with steeper age-related increases in SBP and pulse pressure, particularly beyond 70 years of age and in overweight to obese men.
Authors:
Paul P Giggey; Carrington R Wendell; Alan B Zonderman; Shari R Waldstein
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Intramural     Date:  2010-11-18
Journal Detail:
Title:  American journal of hypertension     Volume:  24     ISSN:  1941-7225     ISO Abbreviation:  Am. J. Hypertens.     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-02-15     Completed Date:  2011-06-15     Revised Date:  2011-06-30    
Medline Journal Info:
Nlm Unique ID:  8803676     Medline TA:  Am J Hypertens     Country:  United States    
Other Details:
Languages:  eng     Pagination:  310-5     Citation Subset:  IM    
Affiliation:
Department of Psychology, University of Maryland, Baltimore, Maryland, USA.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Age Distribution
Aged
Aged, 80 and over
Body Mass Index
Coffee*
Female
Follow-Up Studies
Humans
Hypertension / etiology*
Male
Middle Aged
Chemical
Reg. No./Substance:
0/Coffee

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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