Document Detail

Great vein and right atrial thrombosis in critically ill infants and children with central venous lines.
MedLine Citation:
PMID:  2009803     Owner:  NLM     Status:  MEDLINE    
We performed a retrospective review of echocardiographic data files of infants and children hospitalized in the Newborn and Pediatric Intensive Care Units. Echocardiograms were examined to detect the presence and evolution of great vein and right atrial thrombosis in patients with central venous lines. Thirty-seven patients were identified over a five-year period. Echocardiograms were performed, not routinely, but in response to specific indications including catheter malfunction, thrombocytopenia, persistent chylothorax, bacterial or fungal sepsis, and superior vena cava syndrome. Fifteen of 37 patients died, 13 of them during the hospitalization in which the thrombus was discovered. Thrombolytic agents and surgery were used to treat selected patients, with mixed results. Two of the 22 survivors have significant disability related to the thrombus or complications arising from it. We conclude that great vein and/or right atrial thrombosis is a common complication of central venous catheterization in small infants and children; moreover, the morbidity and mortality relating to this complication is substantial.
W Berman; R R Fripp; S M Yabek; J Wernly; S Corlew
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Chest     Volume:  99     ISSN:  0012-3692     ISO Abbreviation:  Chest     Publication Date:  1991 Apr 
Date Detail:
Created Date:  1991-05-06     Completed Date:  1991-05-06     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0231335     Medline TA:  Chest     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  963-7     Citation Subset:  AIM; IM    
Pediatric Cardiology Associates of New Mexico, Albuquerque.
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MeSH Terms
Catheterization, Central Venous / adverse effects*
Heart Atria
Heart Diseases / etiology*,  mortality,  ultrasonography
Infant, Newborn
Retrospective Studies
Thrombosis / etiology*,  mortality,  ultrasonography
Vena Cava, Superior

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