Document Detail

Great saphenous vein diameter at the saphenofemoral junction and proximal thigh as parameters of venous disease class.
MedLine Citation:
PMID:  23219416     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Great saphenous vein (GSV) incompetence is involved in the majority of cases of varicose disease. Standardised pre-interventional assessment is required to analyse the relative merit of treatment modalities. We weighed GSV diameter measurement at the sapheno-femoral junction (SFJ) against measurement at the proximal thigh 15 cm distal to the groin (PT), established a conversion factor and applied it to selected literature data.
METHODS: Legs with untreated isolated GSV reflux and varices limited to its territory and control legs were studied clinically, with duplex ultrasound and photoplethysmography. GSV diameters were measured at both the SFJ and the PT. A conversion factor was calculated and used to compare published data.
RESULTS: Of 182 legs, 60 had no GSV reflux (controls; group I), 51 had above-knee GSV reflux only (group II) and 71 had GSV reflux above and below knee (group III). GSV diameters in group I measured 7.5 mm (± 1.8) at the SFJ and 3.7 mm (± 0.9) at the PT. In groups II and III, they measured 10.9 mm (± 3.9) at the SFJ and 6.3 mm (± 1.9) at the PT (p < 0.001 each). Measurement at the PT revealed higher sensitivity and specificity to predict reflux and clinical class. Good correlation between sites of measurement (r = 0.77) allowed a conversion factor (SFJ = 1.767 * PT, PT = 0.566*SFJ) to be applied to pre-interventional data of published studies.
CONCLUSIONS: GSV diameter correlates with clinical class, measurement at the PT being more sensitive and more specific than measurement at the SFJ. Applying the conversion factor to published data suggests that some studies included patients with minor disease.
E Mendoza; W Blättler; F Amsler
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Publication Detail:
Type:  Journal Article     Date:  2012-12-07
Journal Detail:
Title:  European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery     Volume:  45     ISSN:  1532-2165     ISO Abbreviation:  Eur J Vasc Endovasc Surg     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-01-21     Completed Date:  2013-03-12     Revised Date:  2013-08-07    
Medline Journal Info:
Nlm Unique ID:  9512728     Medline TA:  Eur J Vasc Endovasc Surg     Country:  England    
Other Details:
Languages:  eng     Pagination:  76-83     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 European Society for Vascular Surgery. Published by Elsevier Ltd. All rights reserved.
Office for Vein Diseases, Wunstorf, Germany.
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MeSH Terms
Analysis of Variance
Chi-Square Distribution
Femoral Vein / pathology*,  physiopathology,  ultrasonography
Middle Aged
Predictive Value of Tests
Saphenous Vein / pathology*,  physiopathology,  ultrasonography
Sensitivity and Specificity
Severity of Illness Index
Ultrasonography, Doppler, Duplex
Varicose Veins / classification,  diagnosis*,  pathology,  physiopathology,  ultrasonography
Venous Insufficiency / classification,  diagnosis*,  pathology,  physiopathology,  ultrasonography
Comment In:
Eur J Vasc Endovasc Surg. 2013 Jul;46(1):151   [PMID:  23628327 ]
Eur J Vasc Endovasc Surg. 2013 Jul;46(1):151   [PMID:  23642519 ]

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