Document Detail


Gravity-dependent perfusion of the lung demonstrated with the FAIRER arterial spin tagging method.
MedLine Citation:
PMID:  11595364     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Magnetic resonance imaging of lung perfusion using an arterial spin tagging (AST) sequence called flow sensitive alternating inversion recovery with an extra RF pulse (FAIRER) was performed in the left and right lateral positions in five volunteers. Coronal slices were obtained and the average intensity of each lung was measured. In both positions, an increase in the intensity of the dependent lung was found (229% for left lateral, 40% for right lateral). No change was seen along an isogravitational plane. Lung volumes were measured in each position to account for the compression of the lungs by the heart. This effect was found to be symmetric and did not contribute to the perfusion gradient. This demonstrates that AST is sensitive to gravity-dependent perfusion gradients in the lung.
Authors:
S D Keilholz; J Knight-Scott; J M Christopher; V M Mai; S S Berr
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Magnetic resonance imaging     Volume:  19     ISSN:  0730-725X     ISO Abbreviation:  Magn Reson Imaging     Publication Date:  2001 Sep 
Date Detail:
Created Date:  2001-10-11     Completed Date:  2001-12-05     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  8214883     Medline TA:  Magn Reson Imaging     Country:  United States    
Other Details:
Languages:  eng     Pagination:  929-35     Citation Subset:  IM; S    
Affiliation:
Engineering Physics Program, School of Engineering, University of Virginia, Charlottesville, VA 22908, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Blood Flow Velocity / physiology
Female
Humans
Image Enhancement
Lung / blood supply*
Magnetic Resonance Imaging / methods*
Male
Posture
Regional Blood Flow / physiology
Spin Labels
Grant Support
ID/Acronym/Agency:
R21 C89633//PHS HHS
Chemical
Reg. No./Substance:
0/Spin Labels

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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