Document Detail

Graves' thyroid ophthalmopathy in Ethiopian patients.
MedLine Citation:
PMID:  11338463     Owner:  NLM     Status:  MEDLINE    
In a prospective study, we evaluated the clinical manifestations, severity, complication and management of Graves' thyroid ophthalmopathy (GTO) in 37 Ethiopian patients. Twenty-seven were females and 10 were males (F:M = 2.7:1). The mean age was 35 years (range 19-70 yrs). The mean duration of ocular symptoms was 33.4 months (range 2-120 months) while the mean duration of hyperthyroid symptoms was 36.2 months (range 6-120 months). GTO was found in 30 (81.1%) hyperthyroid, 1 (2.7%) hypothyroid and 5 (13.5%) euthyroid patients. Upper lid retraction was the most common clinical finding, being detected in 31 (83.8%) of the patients. One (2.7%) patient had marked extraocular muscle involvement, involving the inferior rectus muscle of one eye. Though 18 (48.6) patients had signs of soft tissue inflammation, only 4 (10.8%) required the administration of systemic steroids to control the inflammatory process. None of our patients had sight loss from the complications of GTO. Larger prospective studies are suggested to evaluate both the prevalence and possible racial difference in its clinical presentation.
T Teshome; B Seyoum
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Ethiopian medical journal     Volume:  39     ISSN:  0014-1755     ISO Abbreviation:  Ethiop. Med. J.     Publication Date:  2001 Jan 
Date Detail:
Created Date:  2001-05-07     Completed Date:  2001-05-31     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  0373223     Medline TA:  Ethiop Med J     Country:  Ethiopia    
Other Details:
Languages:  eng     Pagination:  1-8     Citation Subset:  IM    
Department of Ophthalmology, Faculty of Medicine, Addis Ababa University, Addis Ababa.
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MeSH Terms
Age Distribution
Ethiopia / epidemiology
Graves Disease / complications,  diagnosis*,  epidemiology,  therapy*
Middle Aged
Prospective Studies
Severity of Illness Index
Time Factors

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