Document Detail

Graves' disease. Manifestations and therapeutic options.
MedLine Citation:
PMID:  2451239     Owner:  NLM     Status:  MEDLINE    
Graves' disease is the most common cause of hyperthyroidism. Clinical features include thyroid enlargement, eye signs, tachycardia, heat intolerance, emotional lability, weight loss, and hyperkinesis. Three modes of therapy are available. The preferences of the patient and physician are usually prime considerations in devising the therapeutic plan. Radioactive iodine is the most frequently used and safest method of treatment for adults. Antithyroid drugs are preferred for children and pregnant women. Surgery is usually reserved for patients in whom the other forms of treatment are not acceptable. Considerable patient education during the decision-making process enhances the success of the therapeutic plan.
K F McFarland; G Saleeby
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Postgraduate medicine     Volume:  83     ISSN:  0032-5481     ISO Abbreviation:  Postgrad Med     Publication Date:  1988 Mar 
Date Detail:
Created Date:  1988-05-04     Completed Date:  1988-05-04     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  0401147     Medline TA:  Postgrad Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  275-82     Citation Subset:  AIM; IM    
Department of Medicine, Richland Memorial Hospital, Columbia, SC 29203.
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MeSH Terms
Antithyroid Agents / therapeutic use
Graves Disease* / diagnosis,  physiopathology,  therapy
Iodine Radioisotopes / therapeutic use
Thyroid Function Tests
Reg. No./Substance:
0/Antithyroid Agents; 0/Iodine Radioisotopes

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