Document Detail


Grassypeptolides F and G, Cyanobacterial Peptides from Lyngbya majuscula.
MedLine Citation:
PMID:  21806011     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Grassypeptolides F (1) and G (2), bis-thiazoline-containing cyclic depsipeptides with a rare β-amino acid, extensive N-methylation, and a large number of d-amino acids, are reported from an extract of the Palauan cyanobacterium Lyngbya majuscula. Both 1 and 2 were found to have moderate inhibitory activity against the transcription factor AP-1 (IC(50) = 5.2 and 6.0 μM, respectively).
Authors:
Wendy L Popplewell; Ranjala Ratnayake; Jennifer A Wilson; John A Beutler; Nancy H Colburn; Curtis J Henrich; James B McMahon; Tawnya C McKee
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-8-1
Journal Detail:
Title:  Journal of natural products     Volume:  -     ISSN:  1520-6025     ISO Abbreviation:  -     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-8-2     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7906882     Medline TA:  J Nat Prod     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Molecular Targets Laboratory, Center for Cancer Research, NCI-Frederick , Frederick, Maryland 21702-1124, United States.
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