Document Detail


Graphite pneumoconiosis. A review of etiologic and epidemiologic aspects.
MedLine Citation:
PMID:  6314495     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Six hundred and five cases of graphite pneumoconiosis have been reported in the literature. In 39 cases the diagnosis was based on or supported by autopsy or lung biopsy results. Only 14 of the 39 cases were presented with relatively complete documentation as to details about dust exposure. Only one of these completely documented cases suggested that nearly pure graphite may cause graphite pneumoconiosis. Eleven experimental studies on animals dealt with the effect of graphite dust on various tissues, and nine with the effect on lung tissue. The three studies on the effect of pure or nearly pure graphite gave no unanimous conclusion. Five out of six studies dealing with graphite containing silica demonstrated fibrogenic effect on the lungs. Most of the 18 epidemiologic studies of workers exposed to graphite dust are invalid because they do not comply with ordinary methodologic requirements. The present state of knowledge does not exclude the possibility that analytically pure graphite may cause pneumoconiosis although the majority of the evidence indicates that pneumoconiosis is a mixed-dust type of lung reaction.
Authors:
R Hanoa
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Scandinavian journal of work, environment & health     Volume:  9     ISSN:  0355-3140     ISO Abbreviation:  Scand J Work Environ Health     Publication Date:  1983 Aug 
Date Detail:
Created Date:  1983-12-17     Completed Date:  1983-12-17     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7511540     Medline TA:  Scand J Work Environ Health     Country:  FINLAND    
Other Details:
Languages:  eng     Pagination:  303-14     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Carbon*
Graphite*
Humans
Lung / pathology
Pneumoconiosis / epidemiology,  etiology*,  pathology
Silicon Dioxide
Chemical
Reg. No./Substance:
7440-44-0/Carbon; 7631-86-9/Silicon Dioxide; 7782-42-5/Graphite

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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