Document Detail


Graphite nanoplatelets and Caenorhabditis elegans: insights from an in vivo model.
MedLine Citation:
PMID:  22612766     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
We evaluated the toxicity of graphite nanoplatelets (GNPs) in the model organism Caenorhabditis elegans. The GNPs resulted non-toxic by measuring longevity as well as reproductive capability endpoints. An imaging technique based on FTIR mapping was also developed to analyze the GNPs spatial distribution inside the nematodes. Conflicting reports on the in vitro antimicrobial properties of graphene-based nanoparticles prompted us to challenge the host-pathogen system C.elegans-Pseudomonas aeruginosa to assess these findings by an in vivo model.
Authors:
Elena Zanni; Giovanni De Bellis; Maria Paola Bracciale; Alessandra Broggi; Maria Laura Santarelli; Maria Sabrina Sarto; Claudio Palleschi; Daniela Uccelletti
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-5-21
Journal Detail:
Title:  Nano letters     Volume:  -     ISSN:  1530-6992     ISO Abbreviation:  -     Publication Date:  2012 May 
Date Detail:
Created Date:  2012-5-22     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101088070     Medline TA:  Nano Lett     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
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