Document Detail

Graphical tools for RFLP measurement quality assurance: laboratory performance charts.
MedLine Citation:
PMID:  10486949     Owner:  NLM     Status:  MEDLINE    
Forensic restriction fragment length polymorphism analyses typically provide two band size results at each genetic locus for each sample. In collaboration with the member laboratories of the Technical Working Group for DNA Analysis Methods, we have developed graphical techniques that compactly summarize even large numbers of such paired measurements. This paper provides a detailed description of the basic tool, a modified bivariate control chart for data from multiple samples and/or multiple loci. We demonstrate how various modifications and combinations of these "laboratory performance charts" can be used for quality control, quality assurance, and quality demonstration.
K T Gary; D L Duewer; D J Reeder
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Journal of forensic sciences     Volume:  44     ISSN:  0022-1198     ISO Abbreviation:  J. Forensic Sci.     Publication Date:  1999 Sep 
Date Detail:
Created Date:  1999-09-30     Completed Date:  1999-09-30     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0375370     Medline TA:  J Forensic Sci     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  978-82     Citation Subset:  IM    
Biotechnology Division, National Institute of Standards and Technology, Gaithersburg, MD, USA.
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MeSH Terms
Computer Graphics*
DNA Fingerprinting / methods*
K562 Cells
Laboratories / standards*
Polymorphism, Restriction Fragment Length*
Quality Control*
Research Design

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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