| Granulosa cell expression of basal lamina matrices: Call-Exner bodies and focimatrix. | |
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MedLine Citation:
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PMID: 16101042 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A Call-Exner body appears as a rosette of granulosa cells radially disposed (polarized) around an aggregate of extracellular matrix. The function of these bodies is unknown. A newly described matrix, focimatrix, also develops as aggregates of basal lamina-like material between granulosa cells. It appears much later in follicular development, and in a far greater amount than Call-Exner bodies. Its possible role is to reduce the polarity of epithelial granulosa cells allowing them to develop into non-polarized mesenchymal luteal cells upon ovulation of the follicle. Call-Exner bodies may arise from early and isolated expression of focimatrix. |
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Authors:
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H F Irving-Rodgers; R J Rodgers |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Italian journal of anatomy and embryology = Archivio italiano di anatomia ed embriologia Volume: 110 ISSN: 1122-6714 ISO Abbreviation: Ital J Anat Embryol Publication Date: 2005 |
Date Detail:
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Created Date: 2005-08-16 Completed Date: 2005-09-13 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9612303 Medline TA: Ital J Anat Embryol Country: Italy |
Other Details:
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Languages: eng Pagination: 225-30 Citation Subset: IM |
Affiliation:
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Research Centre for Reproductive Health, Department of Obstetrics and Gyneacology, University of Adelaide, Adelaide, Australia. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Basement Membrane / metabolism, ultrastructure* Cattle Cell Differentiation / physiology* Corpus Luteum / growth & development, metabolism, ultrastructure Extracellular Matrix / metabolism, ultrastructure* Extracellular Matrix Proteins / metabolism Female Granulosa Cells / metabolism, ultrastructure* Luteal Cells / metabolism, ultrastructure* Mesoderm / metabolism, ultrastructure Microscopy, Electron, Transmission Oogenesis / physiology Ovarian Follicle / growth & development, metabolism, ultrastructure* Ovulation / physiology Pregnancy |
| Chemical | |
Reg. No./Substance:
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0/Extracellular Matrix Proteins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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