| Granulosa cell apoptosis: conservation of cell signaling in an avian ovarian model system. | |
| | |
MedLine Citation:
|
PMID: 10810204 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Ovarian follicle atresia in all vertebrates studied to date is mediated via apoptosis, a process that is often initiated within the granulosa cell layer. While follicle atresia is considered a normal physiological process to insure the greatest chance for ovulation of fertilizable oocytes, abnormally high rates of atresia result in chronic infertility and/or premature termination of fertility (e.g., menopause). Although the vast majority of research to elucidate the molecular ordering of cell signaling during the process of granulosa cell apoptosis has been conducted in mammalian model systems, there is ample evidence to demonstrate that many of the proteins, enzymes and cell-signaling pathways are common to ovarian follicles from avian species. The following review will discuss evidence for the conservation of cellular processes that regulate the fate of granulosa cells from the avian, versus mammalian, ovary during follicle development. |
| | |
Authors:
|
A L Johnson |
Related Documents
:
|
6627094 - Juvenile hormone increases ouabain-binding capacity of microsomal preparations from vit... 9329864 - Effects of testosterone and oestradiol on [3h]-thymidine incorporation by porcine granu... 10231054 - The same luteinized granulosa-luteal cells from normal and superovulated human chorioni... 3592764 - Ultrastructure of human preovulatory granulosa cells in follicular fluid aspirates. 327754 - Characteristics of the phagocytic process assessed by coulter counter. 10870114 - The interaction of gemcitabine and cytarabine on murine leukemias l1210 or p388 and on ... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.; Review |
Journal Detail:
|
Title: Biological signals and receptors Volume: 9 ISSN: 1422-4933 ISO Abbreviation: Biol Signals Recept Publication Date: 2000 Mar-Apr |
Date Detail:
|
Created Date: 2000-07-19 Completed Date: 2000-07-19 Revised Date: 2007-11-14 |
Medline Journal Info:
|
Nlm Unique ID: 9808792 Medline TA: Biol Signals Recept Country: SWITZERLAND |
Other Details:
|
Languages: eng Pagination: 96-101 Citation Subset: IM |
Copyright Information:
|
Copyright 2000 S. Karger AG, Basel |
Affiliation:
|
Department of Biological Sciences, University of Notre Dame, Notre IN 46556, USA. johnson.128@nd.edu |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Apoptosis / physiology* Birds / physiology* Female Granulosa Cells / physiology* Ovary / cytology, physiology* Signal Transduction / physiology* |
| Grant Support | |
ID/Acronym/Agency:
|
HD36095/HD/NICHD NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Mammalian follicular development and atresia: role of apoptosis.
Next Document: Proteolytic and cellular death mechanisms in ovulatory ovarian rupture.