Document Detail

Granulomatous hepatitis induced by aspirin-kodein analgesics.
MedLine Citation:
PMID:  8772629     Owner:  NLM     Status:  MEDLINE    
Salicylate-kodein is a widely used analgesic agent, particularly in outpatient practice. Salicylates have been incriminated in hepatic injury while kodein may induce biliary spasm. We report here a case of granulomatous hepatitis attributed to prolonged intake of this combination, which has never been reported previously to our knowledge.
A N Elzouki; S Lindgren
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of internal medicine     Volume:  239     ISSN:  0954-6820     ISO Abbreviation:  J. Intern. Med.     Publication Date:  1996 Mar 
Date Detail:
Created Date:  1997-01-06     Completed Date:  1997-01-06     Revised Date:  2010-07-23    
Medline Journal Info:
Nlm Unique ID:  8904841     Medline TA:  J Intern Med     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  279-81     Citation Subset:  IM    
Department of Medicine, Malmö University Hospital, University of Lund, Sweden.
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MeSH Terms
Analgesics / administration & dosage,  adverse effects*
Aspirin / administration & dosage,  adverse effects*
Codeine / administration & dosage,  adverse effects*
Drug Combinations
Drug-Induced Liver Injury / diagnosis,  etiology*
Granuloma / chemically induced*,  diagnosis
Headache / drug therapy
Liver / pathology
Middle Aged
Time Factors
Reg. No./Substance:
0/Analgesics; 0/Drug Combinations; 130320-48-8/aspirin, codeine drug combination; 50-78-2/Aspirin; 76-57-3/Codeine

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