Document Detail


Granulomatous hepatitis as a manifestation of quinidine hypersensitivity.
MedLine Citation:
PMID:  7362358     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Histologic pictures have been conflicting in previous cases of quinidine-associated hepatitis. We report a case of reversible granulomatous hepatitis from quinidine hypersensitivity, with granuloma induction occurring within three days after readministration of quinidine. Fever, urticaria, and mild thrombocytopenia were associated clinical findings. Both light and electron microscopic study results are reported.
Authors:
D A Bramlet; Z Posalaky; R Olson
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Archives of internal medicine     Volume:  140     ISSN:  0003-9926     ISO Abbreviation:  Arch. Intern. Med.     Publication Date:  1980 Mar 
Date Detail:
Created Date:  1980-05-30     Completed Date:  1980-05-30     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  0372440     Medline TA:  Arch Intern Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  395-7     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Biopsy
Drug Hypersensitivity / complications,  etiology*
Drug-Induced Liver Injury / etiology*,  pathology
Female
Granuloma / chemically induced
Humans
Liver / pathology*
Middle Aged
Myocardial Infarction / drug therapy
Quinidine / adverse effects*,  therapeutic use
Ventricular Fibrillation / drug therapy
Chemical
Reg. No./Substance:
56-54-2/Quinidine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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