Document Detail

Granulomatous gastritis: a diagnostic dilemma?
MedLine Citation:
PMID:  18830524     Owner:  NLM     Status:  MEDLINE    
Granulomatous inflammation of the gastrointestinal tract is an uncommon entity; an aetiopathogenic diagnosis can be reached only by combining the morphological examination with clinical and laboratory investigations. We report two cases of granulomatous gastritis: a 27-year-old woman presenting with weight loss and a 55-year-old woman presenting with epigastric pain and vomiting. Upper oesophagastroduodenoscopy in these cases showed antral hyperaemia and histopathology showed non-caseating gastric granulomatous inflammation. Both the cases were extensively worked-up for possible tuberculosis (TB) as the patients lived in an endemic area, before starting steroids for the possibility of Crohn's disease (CD) . The first patient improved but the second patient had a flare of underlying undiagnosed TB. Granulomatous gastritis present a diagnostic challenge for treating physicians because of similar clinical, laboratory and endoscopical features between CD and intestinal TB.
L Kamani; K Mumtaz; N S Azad; W Jafri
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Singapore medical journal     Volume:  49     ISSN:  0037-5675     ISO Abbreviation:  Singapore Med J     Publication Date:  2008 Sep 
Date Detail:
Created Date:  2008-10-02     Completed Date:  2009-07-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0404516     Medline TA:  Singapore Med J     Country:  Singapore    
Other Details:
Languages:  eng     Pagination:  e222-4     Citation Subset:  IM    
Department of Medicine, Aga Khan University Hospital, Stadium Road, Karachi 74800, Pakistan.
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MeSH Terms
Abdominal Pain / diagnosis,  therapy
Crohn Disease / diagnosis,  drug therapy
Diagnosis, Differential
Gastritis / diagnosis*,  microbiology*
Middle Aged
Steroids / therapeutic use
Treatment Outcome
Tuberculosis, Gastrointestinal / diagnosis,  drug therapy
Reg. No./Substance:

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