Document Detail


Granulomatous blepharitis as a sign of Melkersson-Rosenthal syndrome.
MedLine Citation:
PMID:  9224474     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: The objective of our study was to describe the ophthalmic features and histologic eyelid findings of Melkersson-Rosenthal syndrome. DESIGN: Three patients with eyelid edema underwent eyelid biopsy to establish the diagnosis of Melkersson-Rosenthal syndrome. RESULTS: Of the three patients, only one patient manifest the classic triad of facial edema, facial paralysis, and furrowed tongue. Histoloppgically, the eyelid skin in all patients showed characteristic perilymphatic granulomas with marked dermal edema. CONCLUSIONS: The histopathologic features assist in establishing the diagnosis of Melkersson-Rosenthal syndrome in oligo- and monosymptomatic patients. Melkersson-Rosenthal syndrome should be considered in patients presenting with eyelid edema of unknown etiology and biopsy performed.
Authors:
R P Yeatts; W L White
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Ophthalmology     Volume:  104     ISSN:  0161-6420     ISO Abbreviation:  Ophthalmology     Publication Date:  1997 Jul 
Date Detail:
Created Date:  1997-08-12     Completed Date:  1997-08-12     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7802443     Medline TA:  Ophthalmology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1185-9; discussion 1189-90     Citation Subset:  IM    
Affiliation:
Department of Ophthalmology, Bowman Gray School of Medicine of Wake Forest University Winston-Salem, North Carolina, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Biopsy
Blepharitis / complications,  diagnosis*,  pathology
Edema / complications
Eyelid Diseases / complications,  diagnosis*,  pathology
Eyelids / pathology
Female
Granuloma / complications,  diagnosis*,  pathology
Humans
Male
Melkersson-Rosenthal Syndrome / complications,  diagnosis*,  pathology
Middle Aged
Tongue / pathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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