Document Detail

Granulomatous amebic encephalitis caused by acanthamoeba.
MedLine Citation:
PMID:  9225325     Owner:  NLM     Status:  MEDLINE    
Infections arising from free-living amebae are rare. They generally cause recognizable disease only in chronically ill, debilitated patients who are immune suppressed. Only about 70 cases of granulomatous amebic encephalitis have been reported. We present an unusual case of granulomatous encephalitis in a 35-year-old man. Neurologic examination and laboratory tests were inconclusive. CT demonstrated bilateral low-density areas with mild mass effect in the cortex and subcortical white matter, which showed increased signal on T2-weighted MRI. Craniotomy and brain biopsy revealed granulomatous encephalitis with acanthamoeba organisms. Though non-specific, imaging can support the diagnosis of amebic encephalitis and direct biopsy.
J J Sell; F W Rupp; W W Orrison
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Neuroradiology     Volume:  39     ISSN:  0028-3940     ISO Abbreviation:  Neuroradiology     Publication Date:  1997 Jun 
Date Detail:
Created Date:  1997-09-05     Completed Date:  1997-09-05     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  1302751     Medline TA:  Neuroradiology     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  434-6     Citation Subset:  IM    
Department of Radiology, University of New Mexico, Albuquerque 87131-5336, USA.
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MeSH Terms
Acanthamoeba* / isolation & purification
Amebiasis / diagnosis*
Brain / pathology
Cerebral Cortex / pathology
Encephalitis / diagnosis*,  parasitology
Fatal Outcome
Granuloma / diagnosis*
Magnetic Resonance Imaging*
Neurologic Examination
Tomography, X-Ray Computed*

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