Document Detail


Granulocyte transfusions in acute leukaemia. Regeneration of granulopoiesis as determining factor of survival.
MedLine Citation:
PMID:  6940237     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
40 patients with acute leukaemia and severe granulocytopenia were treated with granulocyte transfusions for bacteriologically documented or clinically suspected septicaemia. The patients received an average of 5 transfusions each with 2.1 X 10(10) granulocytes per m2 body surface area per day. 26 patients showed clinical benefit from transfusion therapy as documented by the course of blood cultures, local lesions and fever. Only patients with regeneration of granulopoiesis had definite benefit from granulocyte transfusions. All other patients died ultimately from septicaemia.
Authors:
H Pflieger; R Arnold; S Bhaduri; M Dietrich; H Heimpel; B Kubanek; H Rasche; M Wiesneth
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Scandinavian journal of haematology     Volume:  26     ISSN:  0036-553X     ISO Abbreviation:  Scand J Haematol     Publication Date:  1981 Mar 
Date Detail:
Created Date:  1981-07-23     Completed Date:  1981-07-23     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0404507     Medline TA:  Scand J Haematol     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  215-20     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Acute Disease
Adolescent
Adult
Aged
Blood Transfusion*
Child
Child, Preschool
Granulocytes / transplantation*
Hematopoiesis*
Humans
Leukemia / blood*
Leukemia, Myeloid / blood*
Leukemia, Myeloid, Acute / blood*
Middle Aged
Sepsis / mortality,  therapy

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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