Document Detail

Granulated metrial gland cells in the non-traumatized regions of the uterus of ovariectomized mice with deciduomata maintained on progesterone.
MedLine Citation:
PMID:  3339289     Owner:  NLM     Status:  MEDLINE    
A study has been made of granulated metrial gland (GMG) cells in the non-traumatized regions of the uterus of ovariectomized mice maintained on progesterone and with deciduomata in part of one uterine horn. GMG cells were found in the non-traumatized region of the uterine horns with deciduomata for at least 8 days after induction of the decidual reaction. GMG cells were not found in the contralateral horns without deciduomata. Activation of endometrial stromal cells is characterized by a high mitotic index and, in mice given colchicine, numerous stromal cells were arrested in metaphase in the non-traumatized region of the uterine horns with deciduomata for at least 3 days after induction of the deciduomata. In uterine horns without deciduomata, stromal metaphases were few in number over the same period. A correlation was therefore found between the presence of GMG cells and large numbers of stromal cells in mitosis. There was also a correlation between the absence of GMG cells and small numbers of stromal cells in mitosis. These results are compatible with the hypothesis that the differentiation and maintenance of GMG cells are under the control of endometrial stromal cells.
I Stewart
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of endocrinology     Volume:  116     ISSN:  0022-0795     ISO Abbreviation:  J. Endocrinol.     Publication Date:  1988 Jan 
Date Detail:
Created Date:  1988-03-16     Completed Date:  1988-03-16     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0375363     Medline TA:  J Endocrinol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  11-5     Citation Subset:  IM    
Faculty of Medicine, University of Southampton.
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MeSH Terms
Cell Count
Decidua / cytology*
Endometrium / cytology
Metrial Gland / cytology*
Progesterone / physiology
Uterus / cytology*
Reg. No./Substance:

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