Document Detail

Granular cell basal cell carcinoma.
MedLine Citation:
PMID:  14961915     Owner:  NLM     Status:  MEDLINE    
A 69-year-old woman presented with a 2-year history of a slowly growing tumour on the nose. The clinical diagnosis was basal cell carcinoma (BCC) and a complete excision was performed. Histologically, the tumour had the general features of a BCC but with sheets and nests of cells with granular cytoplasmic changes in the centre of the lesion. A pathological diagnosis of granular cell BCC was made. On immunohistochemical examination, the tumour cells were Ber-EP4, cytokeratin AE1/AE3 and cytokeratin CAM 5.2 positive but S100 protein negative. Only the granular cells were CD68 antigen (monoclonal antibody KP1) positive.
Pavel Dundr; Jirí Stork; Ctibor Povýsil; Frantisek Vosmík
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Australasian journal of dermatology     Volume:  45     ISSN:  1440-0960     ISO Abbreviation:  Australas. J. Dermatol.     Publication Date:  2004 Feb 
Date Detail:
Created Date:  2004-02-13     Completed Date:  2008-06-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0135232     Medline TA:  Australas J Dermatol     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  70-2     Citation Subset:  IM    
Departments of Pathology and Dermatology, First Medical Faculty, Charles University, Prague, Czech Republic.
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MeSH Terms
Aged, 80 and over
Antigens, CD / analysis
Antigens, Differentiation, Myelomonocytic / analysis
Carcinoma, Basal Cell / pathology*
Middle Aged
Skin Neoplasms / pathology*
Tumor Markers, Biological / analysis
Reg. No./Substance:
0/Antigens, CD; 0/Antigens, Differentiation, Myelomonocytic; 0/CD68 antigen, human; 0/Tumor Markers, Biological

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