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Granular cell ameloblastoma showing desmoplasia.
MedLine Citation:
PMID:  22871627     Owner:  NLM     Status:  In-Data-Review    
Our case of ameloblastoma had a surprisingly long 25 year history, with abnormally large dimensions, a multilocular diffuse-mixed radiographic picture, and was histopathologically diagnosed as granular cell ameloblastoma with desmoplasia. To the best of our knowledge, this is the first ameloblastoma ever reported, that has shown combined features of granular cells, desmoplasia, ameloblastic follicles, plexiform, and acanthomatous patterns. The nature of granular cells in this type of tumor and the significance of their presence have also been reviewed. From the studies on aameloblastomas to date, it seems that the old belief that granular cell ameblastoma is the most aggressive variant of ameloblastoma is a myth, and in all probability, granular cells are just a transitional or matured phase in the life cycle of ameloblastomas, starting with normal stellate reticulum-like cells, leading to a production of granules and finally leading to degeneration and formation of cystic areas.
Suchitra Gupta; Harshaminder Grewal; Kunal Sah
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Annals of Saudi medicine     Volume:  32     ISSN:  0975-4466     ISO Abbreviation:  Ann Saudi Med     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-08-08     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8507355     Medline TA:  Ann Saudi Med     Country:  India    
Other Details:
Languages:  eng     Pagination:  537-40     Citation Subset:  IM    
Suchitra Gupta, Department of Oral and Maxillofacial Pathology, Teerthankar Mahaveeer Dental College and Research Centre, TMU, Moradabad, Uttar Pradesh, India, T: 09368558055
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