Document Detail


Grand challenge commentary: Chemical transdifferentiation and regenerative medicine.
MedLine Citation:
PMID:  21079596     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The ability to alter cell identity with small molecules represents a powerful approach to restore biological function lost because of cellular deficiency. Developing this capability through advances in chemical biology could have an enormous impact on human health.
Authors:
Bridget K Wagner
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Nature chemical biology     Volume:  6     ISSN:  1552-4469     ISO Abbreviation:  Nat. Chem. Biol.     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2010-11-16     Completed Date:  2010-12-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101231976     Medline TA:  Nat Chem Biol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  877-9     Citation Subset:  IM    
Affiliation:
Chemical Biology Program, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA. bwagner@broadinstitute.org
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MeSH Terms
Descriptor/Qualifier:
Animals
Cell Transdifferentiation / drug effects*,  physiology
Chemistry / trends*
Diabetes Mellitus / drug therapy,  pathology
Humans
Recovery of Function
Regenerative Medicine / trends*
Signal Transduction / drug effects,  physiology
Small Molecule Libraries
Chemical
Reg. No./Substance:
0/Small Molecule Libraries

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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