Document Detail


Grand challenge commentary: Beyond discovery: probes that see, grab and poke.
MedLine Citation:
PMID:  21079592     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Chemical biology is now able to discover molecules that manipulate virtually any biological target or process. It remains a grand challenge to leverage these molecules into useful probes that can be used to address unsolved problems in biology.
Authors:
Joshua A Kritzer
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Nature chemical biology     Volume:  6     ISSN:  1552-4469     ISO Abbreviation:  Nat. Chem. Biol.     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2010-11-16     Completed Date:  2010-12-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101231976     Medline TA:  Nat Chem Biol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  868-70     Citation Subset:  IM    
Affiliation:
Department of Chemistry, Tufts University, Medford, Massachusetts, USA. joshua.kritzer@tufts.edu
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MeSH Terms
Descriptor/Qualifier:
Cell Biology
Drug Evaluation, Preclinical
Ligands
Protein Engineering
Protein Folding*
RNA, Small Interfering / chemistry
Small Molecule Libraries
Chemical
Reg. No./Substance:
0/Ligands; 0/RNA, Small Interfering; 0/Small Molecule Libraries

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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